Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11981073 | 0.84 | GABRA1 (0.42) | ALDH1A1KDM4ETHRATHRBTRPA1 | |
| SCHEMBL18844142 | 0.82 | SKP2 (0.43) | ALDH1A1KDM4EALOX5THRATHRB | |
| SCHEMBL27299925 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EALOX5GAAMAPT | |
| SCHEMBL11449778 | 0.78 | CYP1A2 (0.43) | ALDH1A1KDM4EALOX5MAPTTHRA | |
| SCHEMBL6301819 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4EALOX5GAAMAPT | |
| SCHEMBL15424212 | 0.77 | ALDH1A1 (0.36) | ALDH1A1KDM4EGAATHRATHRB | |
| SCHEMBL27310969 | 0.77 | MAPT (0.40) | ALDH1A1KDM4EALOX5GAAMAPT | |
| SCHEMBL23890877 | 0.76 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAATHRATHRB | |
| SCHEMBL17880793 | 0.76 | CSNK2A1 (0.44) | ALDH1A1KDM4ETHRATHRBTRPA1 | |
| SCHEMBL12305573 | 0.76 | KDM4E (0.42) | ALDH1A1KDM4EALOX5GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329257-B2 | Compositions and methods for treating tuberculosis | THE BROAD INSTITUTE, INC. (US) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329257-B2 | Compositions and methods for treating tuberculosis | C5, IFNG, TERT | ALDH1A1 1848/4885KDM4E 3217/4885ALOX5 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.