Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12966223 | 0.81 | KDM1A (0.49) | KDM1AHTR4CCR5ALDH1A1 | |
| SCHEMBL12966107 | 0.81 | KDM1A (0.49) | KDM1AHTR4CCR5ALDH1A1 | |
| SCHEMBL21101366 | 0.79 | NR1D1 (0.40) | ALDH1A1 | |
| SCHEMBL23924565 | 0.77 | NR1H2 (0.45) | ALDH1A1 | |
| SCHEMBL17963509 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2HTR4CNR1KCNH2CACNA1I | |
| SCHEMBL18716950 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2HTR4CNR1ALDH1A1TSHR | |
| SCHEMBL31124626 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2HTR4CNR1ALDH1A1TSHR | |
| SCHEMBL21089246 | 0.73 | CACNA1H (0.33) | SMN1; SMN2CNR1ALDH1A1TSHR | |
| SCHEMBL7419075 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2HTR4CNR1KCNH2CACNA1I | |
| SCHEMBL15423826 | 0.71 | KDM1A (0.40) | KDM1AHTR4CCR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |