Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21101366 | 0.91 | NR1D1 (0.40) | NR1H2GPR119MEN1ALDH1A1MAPT | |
| SCHEMBL23931684 | 0.80 | DPP8 (0.31) | — | |
| SCHEMBL30737502 | 0.80 | LMNA (0.39) | ALDH1A1 | |
| SCHEMBL21101363 | 0.80 | USP2 (0.40) | GPR119MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL22989769 | 0.80 | NR1H2 (0.44) | NR1H2NAMPTDDB1CRBNGPR119 | |
| SCHEMBL21101365 | 0.79 | NR1H2 (0.40) | NR1H2NAMPTGPR119MEN1ALDH1A1 | |
| SCHEMBL24032957 | 0.79 | NR1H2 (0.50) | NR1H2NAMPTDDB1CRBNGPR119 | |
| SCHEMBL21101008 | 0.77 | SMN1; SMN2 (0.34) | ALDH1A1 | |
| SCHEMBL16987358 | 0.77 | RORC (0.54) | NR1H2NAMPTRORCTACR1JAK2 | |
| SCHEMBL16987356 | 0.77 | RORC (0.54) | NR1H2NAMPTRORCTACR1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115720580-A | Process for preparing phthalazinone derivatives and intermediates thereof | 伊迪恩斯股份有限公司 | 2023-02-28 | — | — | CN | claimed |
| US-20210323946-A1 | PROCESS FOR PREPARING A PHTHALAZINONE DERIVATIVE AND INTERMEDIATES THEREOF | IDIENCE CO., LTD. (KR) | 2021-10-21 | — | — | US | claimed |
| US-12060345-B2 | Process for preparing a phthalazinone derivative and intermediates thereof | IDIENCE CO., LTD. (KR) | 2024-08-13 | — | — | US | disclosed |
| WO-2024025389-A1 | METHOD FOR PREPARING INTERMEDIATE OF PHTHALAZINONE DERIVATIVE | 아이디언스 주식회사 | 2024-02-01 | — | — | WO | disclosed |
| EP-4139298-A1 | PROCESS FOR PREPARING A PHTHALAZINONE DERIVATIVE AND INTERMEDIATES THEREOF | Idience Co., Ltd. (KR) | 2023-03-01 | — | — | EP | disclosed |
| CN-115720580-A | Process for preparing phthalazinone derivatives and intermediates thereof | 伊迪恩斯股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| WO-2021214502-A1 | PROCESS FOR PREPARING A PHTHALAZINONE DERIVATIVE AND INTERMEDIATES THEREOF | IDIENCE CO., LTD. (KR) | 2021-10-28 | — | — | WO | disclosed |
| US-20210323946-A1 | PROCESS FOR PREPARING A PHTHALAZINONE DERIVATIVE AND INTERMEDIATES THEREOF | IDIENCE CO., LTD. (KR) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12060345-B2 | Process for preparing a phthalazinone derivative and intermediates thereof | AZI2, NISCH, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | NR1H2 4082/4885NAMPT 1520/4885DDB1 3995/4885 |
| US-20210323946-A1 | PROCESS FOR PREPARING A PHTHALAZINONE DERIVATIVE AND INTERMEDIATES THEREOF | NISCH, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DHPS | NR1H2 3421/4885NAMPT 837/4885DDB1 3990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.