Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17754053 | 0.84 | ATM (0.63) | ATMKMT2ACXCR3ALDH1A1MEN1 | |
| SCHEMBL21101177 | 0.83 | CXCR3 (0.65) | KMT2ACXCR3ALDH1A1MEN1SIGMAR1 | |
| SCHEMBL21101334 | 0.83 | ALDH1A1 (0.56) | ATMKMT2ACXCR3ALDH1A1MEN1 | |
| SCHEMBL28829928 | 0.81 | SIGMAR1 (0.57) | ATMKMT2ACXCR3ALDH1A1SIGMAR1 | |
| SCHEMBL12813460 | 0.81 | KDM1A (0.72) | ATMKMT2A | |
| SCHEMBL12813459 | 0.81 | KDM1A (0.72) | ATMKMT2A | |
| SCHEMBL21101180 | 0.80 | CXCR4 (0.47) | CXCR3CXCR4 | |
| SCHEMBL28169202 | 0.79 | CXCR4 (0.68) | KMT2AALDH1A1MEN1SIGMAR1CXCR4 | |
| SCHEMBL16888834 | 0.79 | ATM (0.68) | ATMKMT2ACXCR3ALDH1A1MEN1 | |
| SCHEMBL29767452 | 0.79 | CXCR4 (0.69) | ATMKMT2AALDH1A1MEN1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |