Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28169202 | 0.84 | CXCR4 (0.68) | SIGMAR1KDM1AMAOBCXCR4BCHE | |
| SCHEMBL20907239 | 0.82 | ALDH1A1 (0.51) | SIGMAR1KDM1AMAOBCXCR4BCHE | |
| SCHEMBL21101096 | 0.82 | BCHE (0.62) | SIGMAR1BCHEACHEBACE1CXCR3 | |
| SCHEMBL13800326 | 0.81 | ACHE (0.71) | SIGMAR1BCHEACHEBACE1 | |
| SCHEMBL21101241 | 0.79 | ACHE (0.48) | KDM1AMAOBCXCR4BCHEACHE | |
| SCHEMBL14768798 | 0.79 | CXCR4 (0.47) | SIGMAR1CXCR4ACHEBACE1CCR3 | |
| SCHEMBL23012935 | 0.78 | SIGMAR1 (0.56) | SIGMAR1CXCR4ACHE | |
| SCHEMBL21100972 | 0.78 | CXCR4 (0.49) | SIGMAR1KDM1AMAOBCXCR4BCHE | |
| SCHEMBL21101338 | 0.78 | CXCR4 (0.49) | KDM1AMAOBCXCR4BCHEACHE | |
| SCHEMBL12813681 | 0.78 | KDM1A (0.84) | KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |