Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 8/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21088453 | 0.82 | DRD2 (0.50) | KDM1ADRD2HTR2AHDAC6HDAC1 | |
| SCHEMBL21101096 | 0.81 | BCHE (0.62) | DRD2SLC6A4BCHEACHEBACE1 | |
| SCHEMBL20907239 | 0.81 | ALDH1A1 (0.51) | CXCR4KDM1AMAOBDRD2HTR2A | |
| SCHEMBL28169202 | 0.81 | CXCR4 (0.68) | CXCR4KDM1AMAOBHTR2AHDAC6 | |
| SCHEMBL19725557 | 0.80 | KDM1A (0.67) | CXCR4KDM1AMAOBDRD2HTR2A | |
| SCHEMBL21101256 | 0.80 | SIGMAR1 (0.52) | CXCR4KDM1AMAOBDRD2HTR2A | |
| SCHEMBL21101241 | 0.79 | ACHE (0.48) | CXCR4KDM1AMAOBDRD2HTR2A | |
| SCHEMBL21101233 | 0.78 | SIGMAR1 (0.50) | CXCR4KDM1AMAOBBCHEACHE | |
| SCHEMBL21101338 | 0.78 | CXCR4 (0.49) | CXCR4KDM1AMAOBDRD2HTR2A | |
| SCHEMBL23086760 | 0.77 | DRD2 (0.48) | CXCR4DRD2SLC6A4DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |