Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21101241 | 0.83 | ACHE (0.48) | KCNH2ACHEKDM1AKMT2AMEN1 | |
| SCHEMBL8940292 | 0.81 | ALDH1A1 (0.71) | KDM4EALDH1A1KCNH2GPR119OPRM1 | |
| SCHEMBL12966205 | 0.81 | KDM1A (0.74) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL12813742 | 0.81 | KDM1A (0.74) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL19725557 | 0.81 | KDM1A (0.67) | KDM1AKMT2AMEN1MAOBDRD2 | |
| SCHEMBL21101256 | 0.81 | SIGMAR1 (0.52) | ACHEKDM1AMAOBDRD2HTR2A | |
| SCHEMBL16665723 | 0.80 | ALDH1A1 (0.69) | KDM4EALDH1A1KCNH2GPR119OPRM1 | |
| Hydrochloric Acid SCHEMBL16654841 | 0.79 | ALDH1A1 (0.68) | KDM4EALDH1A1KCNH2GPR119OPRM1 | |
| SCHEMBL28084764 | 0.79 | KDM1A (0.72) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15411661 | 0.79 | KDM1A (0.76) | KDM1AMAOBDRD2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |