Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 8/20 | 0.65 |
| ▸ | FAP | Q12884 | 4/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.48 |
| ▸ | PRMT3 | O60678 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24928106 | 0.85 | FAP (0.73) | PREPFAPDPP7 | |
| SCHEMBL21101632 | 0.81 | PREP (0.66) | PREPFAPDPP7PRMT3 | |
| SCHEMBL21101556 | 0.81 | PREP (0.66) | PREPFAP | |
| SCHEMBL21101629 | 0.80 | PREP (0.64) | PREPFAPDPP7 | |
| SCHEMBL15129792 | 0.79 | PREP (1.00) | PREPFAPDPP7 | |
| SCHEMBL15129791 | 0.79 | PREP (1.00) | PREPFAPDPP7 | |
| SCHEMBL21101486 | 0.79 | PREP (0.67) | PREPFAPDPP7 | |
| SCHEMBL8288849 | 0.78 | PRMT3 (0.56) | PRMT3RAB9A | |
| SCHEMBL21101295 | 0.77 | PREP (0.68) | PREPFAPRAB9A | |
| SCHEMBL21101294 | 0.74 | PREP (0.69) | PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804859-B1 | NOVEL FAP INHIBITORS | UNIV ANTWERPEN (BE) | 2019-06-12 | — | — | EP | disclosed |