Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 4/20 | 0.37 |
| ▸ | CCR8 | P51685 | 4/20 | 0.37 |
| ▸ | CCR5 | P51681 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128666 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1404660 | 0.69 | LMNA (0.47) | ALDH1A1HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3574183 | 0.69 | PTGES (0.51) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28846255 | 0.68 | CCR1 (0.43) | ALDH1A1SMN1; SMN2KMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL15228365 | 0.68 | LMNA (0.45) | ALDH1A1HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2624387 | 0.67 | CCR1 (0.37) | ALDH1A1HTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10968 | 0.66 | — | — | |
| SCHEMBL9277705 | 0.65 | SGMS2 (0.36) | ALDH1A1HTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL15935208 | 0.65 | ALDH1A1 (0.35) | ALDH1A1HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2667239 | 0.65 | SGMS2 (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2993215-B1 | Azabenzimidazo[2,1-a]benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2019-06-19 | — | — | EP | disclosed |