Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 4/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | DRD3 | P35462 | 5/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154050 | 0.81 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BKDM1AMBTD1 | |
| SCHEMBL12813593 | 0.79 | KDM1A (0.77) | KDM1ADRD2MAOBSLC6A4 | |
| SCHEMBL12813596 | 0.79 | KDM1A (0.77) | KDM1ADRD2MAOBSLC6A4 | |
| SCHEMBL13798544 | 0.77 | CHRNA7 (0.50) | MBTD1L3MBTL3L3MBTL1DRD2ACHE | |
| SCHEMBL4071616 | 0.77 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BKDM1AMBTD1 | |
| SCHEMBL19700585 | 0.77 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BKDM1AMBTD1 | |
| SCHEMBL28169202 | 0.77 | CXCR4 (0.68) | KDM1AACHEMAOB | |
| SCHEMBL7841536 | 0.76 | ACHE (0.66) | ACHE | |
| SCHEMBL24123852 | 0.75 | ME3 (0.46) | KDM1AMBTD1L3MBTL3L3MBTL1ACHE | |
| SCHEMBL424881 | 0.74 | CHRNA7 (0.55) | MBTD1L3MBTL3L3MBTL1HRH3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |