Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 6/20 | 0.37 |
| ▸ | NOS3 | P29474 | 5/20 | 0.37 |
| ▸ | NOS1 | P29475 | 5/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10202213 | 0.96 | NCF1 (0.46) | NCF1KDM4EALDH1A1NOS2NOS3 | |
| SCHEMBL23128851 | 0.94 | NCF1 (0.45) | NCF1KDM4EALDH1A1NOS2NOS3 | |
| SCHEMBL26762607 | 0.92 | NCF1 (0.41) | NCF1KDM4EALDH1A1NOS2NOS3 | |
| SCHEMBL13046392 | 0.91 | KDM4E (0.41) | NCF1KDM4EALDH1A1NOS2NOS3 | |
| SCHEMBL10202212 | 0.88 | NCF1 (0.43) | NCF1KDM4EALDH1A1NOS2NOS3 | |
| SCHEMBL24351905 | 0.87 | NCF1 (0.44) | NCF1KDM4EALDH1A1NOS2NOS3 | |
| SCHEMBL13046389 | 0.86 | ADRA1B (0.41) | NCF1KDM4EALDH1A1NOS2NOS3 | |
| SCHEMBL25569150 | 0.85 | KDM4E (0.39) | NCF1KDM4EALDH1A1NOS2NOS3 | |
| SCHEMBL12717990 | 0.84 | NCF1 (0.41) | NCF1KDM4EALDH1A1NOS2NOS3 | |
| SCHEMBL24319183 | 0.84 | NCF1 (0.41) | NCF1KDM4EALDH1A1NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |