SCHEMBL25569150 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	KDM4E	B2RXH2	2/20	0.39

▸	ALDH1A1	P00352	1/20	0.39

▸	NOS2	P35228	7/20	0.38

▸	NOS3	P29474	6/20	0.38

▸	NOS1	P29475	6/20	0.38

▸	NCF1	P14598	1/20	0.38

▸	GNAI3	P08754	1/20	0.34

▸	GNAO1	P09471	1/20	0.34

▸	GNAI1	P63096	1/20	0.34

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	HTR1D	P28221	1/20	0.33

▸	HTR1B	P28222	1/20	0.33

▸	HTR2A	P28223	1/20	0.33

▸	HTR2C	P28335	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10202213	0.89	NCF1 (0.46)	KDM4EALDH1A1NOS2NOS3NOS1
SCHEMBL27267877	0.87	NOS3 (0.38)	NOS2NOS3NOS1SMN1; SMN2HTR1D
SCHEMBL24480387	0.86	SMN1; SMN2 (0.33)	NOS2NOS3NOS1NCF1SMN1; SMN2
SCHEMBL21101619	0.85	NCF1 (0.46)	KDM4EALDH1A1NOS2NOS3NOS1
SCHEMBL13046392	0.85	KDM4E (0.41)	KDM4EALDH1A1NOS2NOS3NOS1
SCHEMBL23128851	0.83	NCF1 (0.45)	KDM4EALDH1A1NOS2NOS3NOS1
SCHEMBL25489002	0.82	NOS3 (0.36)	NOS2NOS3NOS1SMN1; SMN2
SCHEMBL10202212	0.82	NCF1 (0.43)	KDM4EALDH1A1NOS2NOS3NOS1
SCHEMBL24351905	0.81	NCF1 (0.44)	KDM4EALDH1A1NOS2NOS3NOS1
SCHEMBL13046389	0.80	ADRA1B (0.41)	KDM4EALDH1A1NOS2NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023083194-A1	WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF	杭州格博生物医药有限公司	2023-05-19	—	—	WO	disclosed