Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | CES2 | O00748 | 1/20 | 0.66 |
| ▸ | CES1 | P23141 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | KMO | O15229 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL568615 | 0.87 | ALDH1A1 (0.63) | ALDH1A1CES2CES1TP53CYP1A2 | |
| SCHEMBL28341610 | 0.86 | ALDH1A1 (0.67) | ALDH1A1CES2CES1TP53CYP1A2 | |
| SCHEMBL1986403 | 0.86 | CES2 (0.70) | ALDH1A1CES2CES1TP53TSHR | |
| SCHEMBL312393 | 0.84 | CES2 (0.68) | ALDH1A1CES2CES1TP53TSHR | |
| SCHEMBL30512072 | 0.84 | CES2 (0.68) | ALDH1A1CES2CES1TP53TSHR | |
| SCHEMBL27570821 | 0.83 | ALDH1A1 (0.68) | ALDH1A1CES2CES1TP53TSHR | |
| SCHEMBL13785092 | 0.83 | ALDH1A1 (0.63) | ALDH1A1CES2CES1TP53TSHR | |
| SCHEMBL38656427 | 0.83 | ALDH1A1 (0.68) | ALDH1A1CES2CES1TP53TSHR | |
| SCHEMBL8921654 | 0.83 | ALDH1A1 (0.68) | ALDH1A1CES2CES1TP53TSHR | |
| SCHEMBL5016737 | 0.83 | ALDH1A1 (0.58) | ALDH1A1CES2CES1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724957-B | Preparation method of high-temperature-resistant composite cross-linking agent | 东营市宝泽能源科技有限公司 | 2021-06-18 | — | — | CN | claimed |
| CN-112724957-A | Preparation method of high-temperature-resistant composite cross-linking agent | 东营市宝泽能源科技有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-109390156-B | One kind disappears hydrogen agent and preparation method thereof, aluminum electrolytic capacitor electrolyte | 惠州市宙邦化工有限公司 | 2019-11-15 | — | — | CN | claimed |
| CN-109390156-A | One kind disappears hydrogen agent and preparation method thereof, aluminum electrolytic capacitor electrolyte | 惠州市宙邦化工有限公司 | 2019-02-26 | — | — | CN | claimed |
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | claimed |
| EP-2882430-A1 | ANTIBACTERIAL INHIBITORS | McMaster University (CA) | 2015-06-17 | — | — | EP | claimed |
| CN-102516196-B | Alpha, beta-unsaturated ketone compound containing thiazole heterocycle, its preparation method and application | UNIV SHANDONG | 2014-09-03 | — | — | CN | claimed |
| WO-2014022923-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2014-02-13 | — | — | WO | claimed |
| CN-1681470-A | Agent for dyeing keratinous fibres | HENKEL KGAA (DE) | 2005-10-12 | — | — | CN | claimed |
| WO-2004052883-A2 | PROCESS FOR THE SEPARATION OF ENANTIOMERS | HONEYWELL INTERNATIONAL INC. (US) | 2004-06-24 | — | — | WO | claimed |
| US-20040110957-A1 | Process for the synthesis of an antiviral compound | HONEYWELL INTERNATIONAL, INC. (US) | 2004-06-10 | — | — | US | claimed |
| CN-111118076-B | Method for biocatalytically reducing nitro compound | 重庆博腾制药科技股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| WO-2023115621-A1 | METHOD FOR PREPARING Α-HALOGENATED ACETOPHENONE COMPOUND UNDER CATALYSIS OF IONIC LIQUID [TEA][TFOH]2 | 大连大学 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023101326-A1 | NOVEL COMPOUND AS AUTOTAXIN INHIBITOR AND USE THEREOF | 주식회사 넥스트젠바이오사이언스 | 2023-06-08 | — | — | WO | disclosed |
| WO-2021226327-A1 | NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2021-11-11 | — | — | WO | disclosed |
| EP-0163854-A2 | Process for the elimination of fluorescence and cationic or amphoteric aromatic nitro compounds | BAYER AG (DE) | 1985-12-11 | — | — | EP | disclosed |
| US-4315009-A | Antisecretory guanidine derivatives and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-02-09 | — | — | US | disclosed |
| EP-0003640-B1 | ANTISECRETORY GUANIDINE DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-01-27 | — | — | EP | disclosed |
| EP-0003640-A2 | Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-08-22 | — | — | EP | disclosed |
| US-4036838-A | Process for the production of nitro derivatives of aromatic compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110957-A1 | Process for the synthesis of an antiviral compound | EIF2AK2, IRF3, RTF1 | ALDH1A1 2288/4885CES2 1224/4885CES1 573/4885 |
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MRPL21, Q6ZSR9, SPOUT1 | ALDH1A1 3080/4885CES2 3098/4885CES1 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.