SCHEMBL2110180

SCHEMBL2110180

C=C(CCCC(C#N)OC(C)=O)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.34
TBXAS1 P24557 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1985287 0.95 EPHX2 (0.36) EPHX2TBXAS1
SCHEMBL2111108 0.92 TSHR (0.30)
SCHEMBL7183665 0.78 EPHX2 (0.41) EPHX2
SCHEMBL7699097 0.76 FAAH (0.40) EPHX2
SCHEMBL1573329 0.76 FAAH (0.40) EPHX2
SCHEMBL8965442 0.76 TSHR (0.36) EPHX2
SCHEMBL7175617 0.76 TSHR (0.36) EPHX2
Benzene SCHEMBL8964846 0.75 SLC6A3 (0.34) EPHX2
SCHEMBL27768509 0.74 TSHR (0.34)
SCHEMBL7177949 0.72 TSHR (0.34) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7795343-B2 Polymer composition ROHM AND HAAS COMPANY (US) 2010-09-14 US claimed
US-20080139737-A1 Polymer composition ROHM AND HAAS COMPANY 2008-06-12 US claimed
EP-2518109-B1 Stabilised aqueous compositions comprising cationic polymers that deliver paint and primer properties in a coating ROHM & HAAS (US) 2015-06-17 EP disclosed
US-8815997-B2 Aqueous compositions comprising ion exchange resins that deliver paint and primer properties in a coating ROHM AND HAAS COMPANY (US) 2014-08-26 US disclosed
US-8791190-B2 Stabilized aqueous compositions comprising cationic polymers that deliver paint and primer properties in a coating ROHM AND HAAS COMPANY (US) 2014-07-29 US disclosed
EP-2518116-B1 Aqueous compositions comprising ion exchange resins that deliver paint and primer properties in a coating ROHM & HAAS (US) 2014-07-02 EP disclosed
US-20120277333-A1 STABILIZED AQUEOUS COMPOSITIONS COMPRISING CATIONIC POLYMERS THAT DELIVER PAINT AND PRIMER PROPERTIES IN A COATING ROHM AND HAAS COMPANY 2012-11-01 US disclosed
US-20120277334-A1 AQUEOUS COMPOSITIONS COMPRISING ION EXCHANGE RESINS THAT DELIVER PAINT AND PRIMER PROPERTIES IN A COATING ROHM AND HAAS COMPANY 2012-11-01 US disclosed
EP-2518109-A1 Stabilised aqueous compositions comprising cationic polymers that deliver paint and primer properties in a coating Rohm and Haas Company (US) 2012-10-31 EP disclosed
EP-2518116-A1 Aqueous compositions comprising ion exchange resins that deliver paint and primer properties in a coating Rohm and Haas Company (US) 2012-10-31 EP disclosed
US-8158714-B2 Scrub and stain-resistant coating compositions, method for manufacturing thereof and articles comprising the same ROHM AND HAAS COMPANY (US) 2012-04-17 US disclosed
US-8158713-B2 Scrub and stain-resistant coating ROHM AND HAAS COMPANY (US) 2012-04-17 US disclosed
US-7795343-B2 Polymer composition ROHM AND HAAS COMPANY (US) 2010-09-14 US disclosed
US-20090326135-A1 SCRUB AND STAIN-RESISTANT COATING COMPOSITIONS, METHOD FOR MANUFACTURING THEREOF AND ARTICLES COMPRISING THE SAME ROHM AND HAAS (US) 2009-12-31 US disclosed
US-20090171005-A1 Scrub and stain-resistant coating ROHM AND HAAS COMPANY 2009-07-02 US disclosed
US-20090004394-A1 Aqueous polymeric composition KOLLER ANNE DENISE 2009-01-01 US disclosed
US-20080139737-A1 Polymer composition ROHM AND HAAS COMPANY 2008-06-12 US disclosed
US-20070238827-A1 Dirt pickup resistant coating binder having high adhesion to substrates BRADY JEAN M 2007-10-11 US disclosed