Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.33 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21101918 | 0.88 | TACR1 (0.37) | CYP1A2CYP3A4CYP2D6CYP2C19TACR1 | |
| SCHEMBL21101912 | 0.83 | TACR1 (0.35) | CYP1A2CYP2D6CYP2C19TACR1 | |
| SCHEMBL48901 | 0.80 | IDO1 (0.43) | CYP3A4GAAANO1GRNSORT1 | |
| SCHEMBL21101909 | 0.75 | CYP1A2 (0.50) | MEN1CYP1A2CYP2C19KMT2AALDH1A1 | |
| SCHEMBL6492340 | 0.74 | IDO1 (0.48) | CYP1A2CYP2D6CYP2C19TACR1 | |
| SCHEMBL21101779 | 0.74 | FFAR4 (0.46) | DDR1RAPGEF3CNR1 | |
| SCHEMBL21101910 | 0.73 | POLB (0.46) | CYP2C19LMNA | |
| SCHEMBL22775743 | 0.72 | SLC13A3 (0.42) | MEN1PLA2G1BCYP1A2CYP3A4GAA | |
| SCHEMBL10153376 | 0.72 | RXRA (0.54) | MEN1PLA2G1BCYP1A2CYP3A4GAA | |
| SCHEMBL4286759 | 0.72 | RXRA (0.49) | MEN1CYP1A2CYP2C19KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019111225-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF NON‑ALCOHOLIC STEATOHEPATITIS | AVALIV THERAPEUTICS (US) | 2019-06-13 | — | — | WO | disclosed |