Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | S100A4 | P26447 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21102583 | 0.96 | CYP1A2 (0.48) | ALDH1A1MAPK1S100A4CYP2A6CYP1A2 | |
| SCHEMBL571071 | 0.90 | ALDH1A1 (0.54) | ALDH1A1MAPK1S100A4CYP2A6CYP1A2 | |
| SCHEMBL21207790 | 0.87 | CYP1A2 (0.52) | ALDH1A1MAPK1S100A4CYP2A6CYP1A2 | |
| SCHEMBL30223349 | 0.87 | ALDH1A1 (0.57) | ALDH1A1MAPK1S100A4CYP2A6CYP1A2 | |
| SCHEMBL20023629 | 0.86 | CYP1A2 (0.54) | ALDH1A1MAPK1S100A4CYP2A6CYP1A2 | |
| SCHEMBL31465791 | 0.86 | S100A4 (0.50) | ALDH1A1MAPK1S100A4CYP2A6KMT2A | |
| SCHEMBL25962009 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPK1S100A4CYP2A6CYP1A2 | |
| SCHEMBL26668634 | 0.84 | CYP2A6 (0.44) | ALDH1A1MAPK1CYP2A6CYP1A2PTGS2 | |
| SCHEMBL31677417 | 0.84 | S100A4 (0.57) | ALDH1A1S100A4CYP2A6CYP1A2PTGS2 | |
| SCHEMBL31677416 | 0.84 | S100A4 (0.57) | ALDH1A1MAPK1S100A4CYP2A6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466701-A | Preparation method of organic luminescent material intermediate 2-chlorobenzo [9,10] phenanthrene | 奥盖尼克材料(苏州)有限公司 | 2024-01-30 | — | — | CN | disclosed |
| US-20200308129-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-10-01 | — | — | US | disclosed |
| WO-2019115577-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308129-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | DDC, CHRM5, AFF2 | ALDH1A1 1738/4885MAPK1 3334/4885S100A4 1134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.