SCHEMBL571071

SCHEMBL571071

Clc1ccc(-c2ccccc2)c(Br)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
MAPK1 P28482 2/20 0.54
CYP1A2 P05177 1/20 0.46
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
RXFP1 Q9HBX9 1/20 0.43
TP53 P04637 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP2A6 P11509 1/20 0.43
KDM4E B2RXH2 2/20 0.42
HSD11B1 P28845 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41
S100A4 P26447 1/20 0.41
CSNK2A1 P68400 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20023629 0.96 CYP1A2 (0.54) ALDH1A1MAPK1CYP1A2KMT2AMEN1
SCHEMBL22480708 0.90 CYP1A2 (0.46) ALDH1A1MAPK1CYP1A2KMT2AMEN1
SCHEMBL21102413 0.90 ALDH1A1 (0.48) ALDH1A1MAPK1CYP1A2KMT2AMEN1
SCHEMBL21102583 0.87 CYP1A2 (0.48) ALDH1A1MAPK1CYP1A2KMT2AMEN1
SCHEMBL21031787 0.86 AHR (0.45) ALDH1A1MAPK1CYP1A2CYP2A6HSD11B1
SCHEMBL30805707 0.86 AHR (0.45) ALDH1A1MAPK1CYP1A2CYP2A6HSD11B1
SCHEMBL30523588 0.86 CYP1A2 (0.58) ALDH1A1MAPK1CYP1A2KMT2AMEN1
SCHEMBL26668634 0.85 CYP2A6 (0.44) ALDH1A1MAPK1CYP1A2KMT2AMEN1
SCHEMBL20687339 0.85 TDO2 (0.43) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL30523580 0.84 ALOX5 (0.47) ALDH1A1MAPK1CYP1A2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114230433-B Synthesis method of 2-bromo-4 '-chloro-1, 1' -biphenyl 郑州海阔光电材料有限公司 2023-10-20 CN claimed
CN-116768785-A Synthesis method of spirofluorene-containing indole derivative structure 西安欧得光电材料有限公司 2023-09-19 CN claimed
CN-114230433-A Synthetic method of 2-bromo-4 '-chloro-1, 1' -biphenyl 郑州海阔光电材料有限公司 2022-03-25 CN claimed
CN-119977923-A Main body material, organic electroluminescent material containing double main bodies and organic electroluminescent device 吉林奥来德光电材料股份有限公司 2025-05-13 CN disclosed
US-12289988-B2 Nitrogen-containing compounds, electronic elements and electronic devices SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2025-04-29 US disclosed
CN-118301963-A Amine-containing compound, and light-emitting device and electronic device each containing amine-containing compound 三星显示有限公司 2024-07-05 CN disclosed
CN-112538047-B Organic compound with symmetrical iso-substituted azaspirobifluorene structure and application thereof 常州强力电子新材料股份有限公司 2024-06-11 CN disclosed
CN-112538046-B Organic compound with aza-spiro-bifluorene structure and application thereof 常州强力电子新材料股份有限公司 2024-06-07 CN disclosed
US-20240147853-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-05-02 US disclosed
CN-110785401-B Organic compound and organic electroluminescent element comprising same 斗山索如始株式会社 2024-03-29 CN disclosed
CN-117777120-A Compound for organic electric element, organic electric element using same, and electronic device using same 德山新勒克斯有限公司 2024-03-29 CN disclosed
CN-105367482-A N-acylsulfamide apoptosis accelerator ASTRAZENECA AB 2016-03-02 CN disclosed
CN-103153954-B N-acylsulfonamide apoptosis promoters ASTRAZENECA AB (SE) 2015-11-25 CN disclosed
US-20140353554-A1 POLYMERIC PRECURSORS FOR PRODUCING GRAPHENE NANORIBBONS AND METHODS FOR PREPARING THEM BASF SE (DE) 2014-12-04 US disclosed
EP-2794476-A1 POLYMERIC PRECURSORS FOR PRODUCING GRAPHENE NANORIBBONS AND METHODS FOR PREPARING THEM BASF SE (DE) 2014-10-29 EP disclosed
WO-2013093756-A1 POLYMERIC PRECURSORS FOR PRODUCING GRAPHENE NANORIBBONS AND METHODS FOR PREPARING THEM BASF SE (DE) 2013-06-27 WO disclosed
EP-2601177-A1 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS AstraZeneca AB (SE) 2013-06-12 EP disclosed
CN-103153954-A N-acylsulfonamide apoptosis promoters ASTRAZENECA AB 2013-06-12 CN disclosed
WO-2012017251-A1 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS ASTRAZENECA AB (SE) 2012-02-09 WO disclosed
CN-101072561-A Diaminoalkane aspartic protease inhibitors VITAE PHARMACEUTICALS INC (US) 2007-11-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12289988-B2 Nitrogen-containing compounds, electronic elements and electronic devices NPPA, NES, INA ALDH1A1 1874/4885MAPK1 1291/4885CYP1A2 1044/4885
US-20140353554-A1 POLYMERIC PRECURSORS FOR PRODUCING GRAPHENE NANORIBBONS AND METHODS FOR PREPARING THEM HCCS, CBR1, SCO2 ALDH1A1 1143/4885MAPK1 1582/4885CYP1A2 99/4885
US-20240147853-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 ALDH1A1 10/4885MAPK1 304/4885CYP1A2 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.