Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702910 | 0.96 | PLA2G2A (0.56) | KMT2APLA2G2AL3MBTL1GAAPLK1 | |
| SCHEMBL22779381 | 0.88 | KAT6A (0.53) | KMT2APLA2G2AL3MBTL1GAAPLK1 | |
| SCHEMBL9970987 | 0.86 | PLA2G2A (0.64) | PLA2G2AL3MBTL1GAAALDH1A1MAPT | |
| SCHEMBL8370828 | 0.85 | L3MBTL1 (0.44) | KMT2APLA2G2AL3MBTL1GAAPLK1 | |
| SCHEMBL11387851 | 0.85 | PLA2G2A (0.72) | KMT2APLA2G2AL3MBTL1GAA | |
| SCHEMBL17109507 | 0.84 | PLA2G2A (0.71) | KMT2APLA2G2AL3MBTL1PLK1NR1H4 | |
| SCHEMBL10498963 | 0.83 | PLA2G2A (0.75) | PLA2G2AL3MBTL1GAA | |
| SCHEMBL9402858 | 0.83 | PLA2G2A (0.75) | PLA2G2AL3MBTL1GAA | |
| SCHEMBL10497457 | 0.83 | PLA2G2A (0.75) | PLA2G2AL3MBTL1GAA | |
| SCHEMBL19565362 | 0.83 | PLA2G2A (0.75) | PLA2G2AL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190192674-A1 | NUCLEIC ACID CONJUGATE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190192674-A1 | NUCLEIC ACID CONJUGATE | M6PR, NSUN2, NSUN3 | KMT2A 577/4885PLA2G2A 4086/4885L3MBTL1 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.