SCHEMBL21111046

SCHEMBL21111046

COC(=O)c1ccc(C(F)(F)F)cc1NS(=O)(=O)C(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.57
KDM4E B2RXH2 4/20 0.49
HSD17B10 Q99714 4/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
ACLY P53396 2/20 0.47
ALDH1A1 P00352 4/20 0.47
HPGD P15428 3/20 0.47
MAPT P10636 1/20 0.47
MCL1 Q07820 1/20 0.46
KDM1A O60341 2/20 0.44
PARP14 Q460N5 1/20 0.41
PTPN11 Q06124 1/20 0.41
ERAP2 Q6P179 1/20 0.41
ERAP1 Q9NZ08 1/20 0.41
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
AVPR2 P30518 1/20 0.40
GPR27 Q9NS67 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3738491 0.89 CFTR (0.54) CFTRKDM4EHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL9687893 0.87 KDM4E (0.65) CFTRKDM4EHSD17B10SMN1; SMN2ACLY
SCHEMBL2080103 0.86 ACLY (0.49) CFTRKDM4EHSD17B10SMN1; SMN2ACLY
SCHEMBL21111044 0.84 ACLY (0.64) KDM4EHSD17B10ACLYALDH1A1HPGD
SCHEMBL23141175 0.84 CFTR (0.55) CFTRKDM4EHSD17B10SMN1; SMN2ACLY
SCHEMBL23141176 0.82 ALDH1A1 (0.61) CFTRKDM4EHSD17B10SMN1; SMN2ACLY
SCHEMBL1450639 0.81 FFAR4 (0.57) CFTRKDM4EHSD17B10SMN1; SMN2ACLY
SCHEMBL23141173 0.80 KDM1A (0.56) CFTRKDM4EHSD17B10ACLYALDH1A1
SCHEMBL5300106 0.80 KDM1A (0.71) CFTRKDM4EHSD17B10ACLYALDH1A1
SCHEMBL31518457 0.80 TSHR (0.57) KDM4EHSD17B10ALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10793520-B2 Sulfonylaminobenzamide compound and pest control agent NIPPON SODA CO., LTD. (JP) 2020-10-06 US disclosed
US-10793520-B2 Sulfonylaminobenzamide compound and pest control agent NIPPON SODA CO., LTD. (JP) 2020-10-06 US disclosed
US-20190225577-A1 SULFONYLAMINOBENZAMIDE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2019-07-25 US disclosed
US-20190225577-A1 SULFONYLAMINOBENZAMIDE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2019-07-25 US disclosed
EP-3508475-A1 SULFONYLAMINO BENZAMIDE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2019-07-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225577-A1 SULFONYLAMINOBENZAMIDE COMPOUND AND PEST CONTROL AGENT CBR3, CBR1, HRH2 CFTR 634/4885KDM4E 1440/4885HSD17B10 2066/4885
US-10793520-B2 Sulfonylaminobenzamide compound and pest control agent CBR3, CBR1, HRH2 CFTR 634/4885KDM4E 1440/4885HSD17B10 2066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.