Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CFTR | P13569 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226777 | 0.89 | KDM4E (0.59) | KDM4EHSD17B10SMN1; SMN2CFTRTSHR | |
| SCHEMBL3744782 | 0.89 | CFTR (0.55) | KDM4EHSD17B10SMN1; SMN2CFTRTSHR | |
| SCHEMBL21111046 | 0.87 | CFTR (0.57) | KDM4EHSD17B10SMN1; SMN2CFTRACLY | |
| SCHEMBL7552302 | 0.85 | ACLY (0.64) | KDM4EHSD17B10SMN1; SMN2ACLYHPGD | |
| SCHEMBL23141175 | 0.85 | CFTR (0.55) | KDM4EHSD17B10SMN1; SMN2CFTRACLY | |
| SCHEMBL23141176 | 0.83 | ALDH1A1 (0.61) | KDM4EHSD17B10SMN1; SMN2CFTRACLY | |
| SCHEMBL1450639 | 0.82 | FFAR4 (0.57) | KDM4EHSD17B10SMN1; SMN2CFTRACLY | |
| SCHEMBL7559128 | 0.82 | KDM4E (0.63) | KDM4EHSD17B10SMN1; SMN2CFTRTSHR | |
| SCHEMBL3378756 | 0.81 | KIF11 (0.54) | KDM4EHSD17B10SMN1; SMN2CFTRTSHR | |
| SCHEMBL23141173 | 0.81 | KDM1A (0.56) | KDM4EHSD17B10CFTRACLYHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506709-A1 | ARTHROPODICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-07 | — | — | EP | disclosed |
| WO-1991008207-A1 | ARTHROPODICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-13 | — | — | WO | disclosed |