SCHEMBL21111044

SCHEMBL21111044

O=C(O)c1ccc(C(F)(F)F)cc1NS(=O)(=O)C(F)(F)F

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACLY P53396 7/20 0.64
KDM1A O60341 3/20 0.60
GRIK1 P39086 2/20 0.52
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HPGD P15428 2/20 0.51
HSD17B10 Q99714 2/20 0.51
MEN1 O00255 1/20 0.51
GAA P10253 1/20 0.51
KMT2A Q03164 1/20 0.51
TAS2R14 Q9NYV8 3/20 0.50
CCR1 P32246 1/20 0.46
CCR2 P41597 1/20 0.46
AKR1B1 P15121 1/20 0.46
AKR1C4 P17516 1/20 0.46
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
AKR1C1 Q04828 1/20 0.46
USP2 O75604 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3738629 0.88 KDM1A (0.65) ACLYKDM1AKDM4EALDH1A1HPGD
SCHEMBL2080103 0.87 ACLY (0.49) ACLYKDM1AKDM4EALDH1A1HPGD
SCHEMBL7552302 0.85 ACLY (0.64) ACLYKDM1AGRIK1KDM4EALDH1A1
SCHEMBL21111046 0.84 CFTR (0.57) ACLYKDM1AKDM4EALDH1A1HPGD
SCHEMBL21111050 0.82 GPR27 (0.52)
SCHEMBL23877488 0.81 ACLY (0.60) ACLYKDM1AGRIK1KDM4EALDH1A1
SCHEMBL23141184 0.81 ACLY (0.60) ACLYKDM1AGRIK1KDM4EALDH1A1
SCHEMBL3988524 0.81 ACLY (0.75) ACLYKDM1AALDH1A1MEN1GAA
SCHEMBL5666108 0.81 CCR2 (0.72) ACLYMEN1GAAKMT2ATAS2R14
SCHEMBL23141185 0.79 ACLY (0.57) ACLYKDM1AALDH1A1HSD17B10TAS2R14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10793520-B2 Sulfonylaminobenzamide compound and pest control agent NIPPON SODA CO., LTD. (JP) 2020-10-06 US disclosed
US-10793520-B2 Sulfonylaminobenzamide compound and pest control agent NIPPON SODA CO., LTD. (JP) 2020-10-06 US disclosed
US-20190225577-A1 SULFONYLAMINOBENZAMIDE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2019-07-25 US disclosed
US-20190225577-A1 SULFONYLAMINOBENZAMIDE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2019-07-25 US disclosed
EP-3508475-A1 SULFONYLAMINO BENZAMIDE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2019-07-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225577-A1 SULFONYLAMINOBENZAMIDE COMPOUND AND PEST CONTROL AGENT CBR3, CBR1, HRH2 ACLY 1246/4885KDM1A 685/4885GRIK1 2850/4885
US-10793520-B2 Sulfonylaminobenzamide compound and pest control agent CBR3, CBR1, HRH2 ACLY 1246/4885KDM1A 685/4885GRIK1 2850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.