Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21111285 | 1.00 | RIPK1 (0.41) | RIPK1USP30 | |
| SCHEMBL17312488 | 0.92 | RIPK1 (0.41) | RIPK1 | |
| SCHEMBL17312486 | 0.92 | RIPK1 (0.41) | RIPK1 | |
| SCHEMBL18409596 | 0.86 | RIPK1 (0.41) | RIPK1 | |
| SCHEMBL18409597 | 0.86 | RIPK1 (0.41) | RIPK1 | |
| SCHEMBL21111151 | 0.85 | USP30 (0.42) | RIPK1USP30 | |
| SCHEMBL21111150 | 0.85 | USP30 (0.42) | RIPK1USP30 | |
| SCHEMBL17312431 | 0.82 | KIF11 (0.40) | RIPK1 | |
| SCHEMBL17312429 | 0.82 | KIF11 (0.40) | RIPK1 | |
| SCHEMBL17312438 | 0.82 | HPGD (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508484-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-07-10 | — | — | EP | disclosed |