Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21113820 | 1.00 | PARP1 (0.44) | PARP1MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL19874849 | 0.86 | PARP1 (0.46) | PARP1ALDH1A1KDM4EHPGDMAOA | |
| SCHEMBL19874865 | 0.86 | PARP1 (0.46) | PARP1ALDH1A1KDM4EHPGDMAOA | |
| SCHEMBL4829723 | 0.75 | PARP1 (0.74) | PARP1MAOAMAOB | |
| SCHEMBL7151532 | 0.72 | PARP1 (0.49) | PARP1MAPTLMNAALDH1A1ALOX15 | |
| SCHEMBL30456122 | 0.71 | PARP1 (0.41) | PARP1ALDH1A1KDM4EALOX15G6PD | |
| SCHEMBL19886737 | 0.71 | PARP1 (0.41) | PARP1ALDH1A1KDM4EALOX15G6PD | |
| SCHEMBL23642797 | 0.71 | PARP1 (0.44) | PARP1MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL673401 | 0.71 | PARP1 (0.44) | PARP1MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL18089409 | 0.71 | PARP1 (0.44) | PARP1MAPTLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10618918-B2 | Substituted boronic acids as antimicrobials | QPEX BIOPHARMA, INC. (US) | 2020-04-14 | — | — | US | disclosed |
| US-20190211037-A1 | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES IN ANTIMICROBIAL TREATMENT | REMPEX PHARMACEUTICALS, INC. | 2019-07-11 | — | — | US | disclosed |
| US-20190211037-A1 | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES IN ANTIMICROBIAL TREATMENT | REMPEX PHARMACEUTICALS, INC. | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10618918-B2 | Substituted boronic acids as antimicrobials | ABCB11, BRS3, SLC10A2 | PARP1 3697/4885MAPT 3761/4885LMNA 1508/4885 |
| US-20190211037-A1 | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES IN ANTIMICROBIAL TREATMENT | BTD, BCL6B, BPGM | PARP1 1586/4885MAPT 2616/4885LMNA 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.