Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 15/20 | 0.39 |
| ▸ | FEN1 | P39748 | 14/20 | 0.39 |
| ▸ | RORC | P51449 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21122112 | 0.85 | RORC (0.38) | ALOX5APFEN1RORC | |
| SCHEMBL21163150 | 0.84 | RORC (0.38) | ALOX5APFEN1RORC | |
| SCHEMBL21113968 | 0.82 | ALOX5AP (0.36) | ALOX5APFEN1RORC | |
| SCHEMBL21113973 | 0.81 | ALOX5AP (0.38) | ALOX5APFEN1RORC | |
| SCHEMBL21114053 | 0.77 | ALOX5AP (0.35) | ALOX5APFEN1RORC | |
| SCHEMBL21114165 | 0.76 | FEN1 (0.34) | ALOX5APFEN1 | |
| SCHEMBL21114068 | 0.75 | RXRA (0.35) | ALOX5APFEN1 | |
| SCHEMBL21113951 | 0.75 | SCN9A (0.36) | ALOX5APFEN1RORC | |
| SCHEMBL21114142 | 0.73 | SCN9A (0.36) | ALOX5APFEN1RORC | |
| SCHEMBL21114098 | 0.72 | ALOX5AP (0.42) | ALOX5APFEN1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190210973-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF CYSTIC FIBROSIS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190210973-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF CYSTIC FIBROSIS | CFTR, SLC26A4, SERPINB1 | ALOX5AP 1319/4885FEN1 1905/4885RORC 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.