Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ATIC | P31939 | 2/20 | 0.49 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | BRD1 | O95696 | 4/20 | 0.48 |
| ▸ | BRPF1 | P55201 | 4/20 | 0.48 |
| ▸ | BRPF3 | Q9ULD4 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281538 | 0.81 | KDM1A (0.68) | KDM1ACYP19A1ARBRD4CA1 | |
| SCHEMBL6555449 | 0.81 | KDM1A (0.68) | KDM1ACYP19A1ARBRD4CA1 | |
| SCHEMBL7572500 | 0.81 | CES1 (0.73) | KDM1ACYP19A1ARBRD4CA1 | |
| SCHEMBL6554559 | 0.81 | CES1 (0.73) | KDM1ACYP19A1ARBRD4CA1 | |
| SCHEMBL96241 | 0.81 | KDM1A (0.64) | KDM1ACYP19A1ARBRD4CA1 | |
| SCHEMBL27888183 | 0.81 | CA1 (0.65) | KDM1ACYP19A1ARBRD4CA1 | |
| SCHEMBL14645822 | 0.80 | CYP19A1 (0.75) | KDM1ACYP19A1ARCA1CA2 | |
| SCHEMBL7572258 | 0.80 | CYP19A1 (0.75) | KDM1ACYP19A1ARCA1CA2 | |
| SCHEMBL21114799 | 0.79 | CA12 (0.64) | CA1CA2TP53MAPT | |
| SCHEMBL21114782 | 0.79 | NPSR1 (0.54) | ARIDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240173287-A1 | Application Of PI4KIIIA Protein And Related Membrane Protein Complex In Treating Alzheimer's Disease | JIANGSU NUO-BETA PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2024-05-30 | — | — | US | disclosed |
| US-11766420-B2 | Application of PI4KIIIA protein and related membrane protein complex in treating alzheimer's disease | Jiangsu Nuo-Beta Pharmaceutical Technology Co. Ltd. (CN) | 2023-09-26 | — | — | US | disclosed |
| US-11236378-B2 | Method for screening drug and therapeutic targets used for treating Alzheimer's disease | Jiangsu Nuo-Beta Pharmaceutical Technology Co. Ltd. (CN) | 2022-02-01 | — | — | US | disclosed |
| US-20190314321-A1 | Application Of PI4KIIIA Protein And Related Membrane Protein Complex In Treating Alzheimer's Disease | JIANGSU NUO-BETA PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2019-10-17 | — | — | US | disclosed |
| US-20190211371-A1 | Method For Screening Drug And Therapeutic Targets Used For Treating Alzheimer's Disease | JIANGSU NUO-BETA PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190314321-A1 | Application Of PI4KIIIA Protein And Related Membrane Protein Complex In Treating Alzheimer's Disease | PI4K2A, PI4K2B, PIP4K2A | KDM1A 4151/4885CYP19A1 3403/4885AR 2393/4885 |
| US-11236378-B2 | Method for screening drug and therapeutic targets used for treating Alzheimer's disease | PSD, TBRG4, ACTR3 | KDM1A 4501/4885CYP19A1 3510/4885AR 3111/4885 |
| US-11766420-B2 | Application of PI4KIIIA protein and related membrane protein complex in treating alzheimer's disease | PI4K2A, PI4K2B, PIP4K2A | KDM1A 4151/4885CYP19A1 3403/4885AR 2393/4885 |
| US-20240173287-A1 | Application Of PI4KIIIA Protein And Related Membrane Protein Complex In Treating Alzheimer's Disease | PI4K2A, PI4K2B, PIP4K2A | KDM1A 4151/4885CYP19A1 3403/4885AR 2393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.