Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2005010 | 0.87 | CA12 (0.81) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL21114817 | 0.83 | CA1 (0.65) | CA1CA2ALDH1A1MAPTLMNA | |
| SCHEMBL21114782 | 0.83 | NPSR1 (0.54) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL19921057 | 0.82 | KMT2A (0.69) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL21114823 | 0.82 | GAA (0.69) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL9001311 | 0.82 | CA12 (0.72) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL11705580 | 0.82 | MEN1 (0.86) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL19921033 | 0.79 | CA2 (0.68) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL21114779 | 0.79 | KDM1A (0.61) | CA1CA2MAPTTP53 | |
| SCHEMBL19921050 | 0.79 | MEN1 (0.55) | CA1CA2ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290514-B1 | APPLICATION OF PI4KIII.ALPHA PROTEIN AND RELATED MEMBRANE PROTEIN COMPLEX IN TREATING ALZHEIMER'S DISEASE | JIANGSU NUO BETA PHARMACEUTICAL TECH CO LTD (CN) | 2025-02-26 | — | — | EP | disclosed |
| US-20240173287-A1 | Application Of PI4KIIIA Protein And Related Membrane Protein Complex In Treating Alzheimer's Disease | JIANGSU NUO-BETA PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2024-05-30 | — | — | US | disclosed |
| US-11766420-B2 | Application of PI4KIIIA protein and related membrane protein complex in treating alzheimer's disease | Jiangsu Nuo-Beta Pharmaceutical Technology Co. Ltd. (CN) | 2023-09-26 | — | — | US | disclosed |
| US-11236378-B2 | Method for screening drug and therapeutic targets used for treating Alzheimer's disease | Jiangsu Nuo-Beta Pharmaceutical Technology Co. Ltd. (CN) | 2022-02-01 | — | — | US | disclosed |
| US-20190314321-A1 | Application Of PI4KIIIA Protein And Related Membrane Protein Complex In Treating Alzheimer's Disease | JIANGSU NUO-BETA PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2019-10-17 | — | — | US | disclosed |
| US-20190211371-A1 | Method For Screening Drug And Therapeutic Targets Used For Treating Alzheimer's Disease | JIANGSU NUO-BETA PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190314321-A1 | Application Of PI4KIIIA Protein And Related Membrane Protein Complex In Treating Alzheimer's Disease | PI4K2A, PI4K2B, PIP4K2A | CA12 4831/4885CA1 3473/4885CA2 4091/4885 |
| US-11236378-B2 | Method for screening drug and therapeutic targets used for treating Alzheimer's disease | PSD, TBRG4, ACTR3 | CA12 4838/4885CA1 3826/4885CA2 4161/4885 |
| US-11766420-B2 | Application of PI4KIIIA protein and related membrane protein complex in treating alzheimer's disease | PI4K2A, PI4K2B, PIP4K2A | CA12 4831/4885CA1 3473/4885CA2 4091/4885 |
| US-20240173287-A1 | Application Of PI4KIIIA Protein And Related Membrane Protein Complex In Treating Alzheimer's Disease | PI4K2A, PI4K2B, PIP4K2A | CA12 4831/4885CA1 3473/4885CA2 4091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.