Sugi Predict

Sugi Predict / Compounds / SCHEMBL211159

SCHEMBL211159

SCHEMBL211159

CCCCC(O)OS(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TP53 P04637 1/20 0.41
▸ RECQL P46063 1/20 0.36
▸ FDPS P14324 1/20 0.35
▸ CA2 P00918 4/20 0.35
▸ CA1 P00915 2/20 0.35
▸ MAPK1 P28482 1/20 0.34
▸ GPR84 Q9NQS5 3/20 0.33
▸ FFAR1 O14842 1/20 0.33
▸ PTPN1 P18031 1/20 0.33
▸ CDC25A P30304 1/20 0.33
▸ DUSP3 P51452 1/20 0.33
▸ DPP7 Q9UHL4 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22749156 0.92 TP53 (0.47) TP53FDPSGPR84FFAR1
SCHEMBL5081945 0.90 TP53 (0.46) TP53FDPSGPR84FFAR1
SCHEMBL710698 0.86 TP53 (0.34) TP53FDPSCA2CA1
Ammonia Solution, Strong SCHEMBL11352450 0.84 TP53 (0.33) TP53FDPSCA2CA1
SCHEMBL28288117 0.77 CA1 (0.34) CA2CA1
SCHEMBL22749155 0.77 GPR84 (0.45) TP53FDPSGPR84FFAR1
SCHEMBL1565006 0.77 PTPN1 (0.40) TP53RECQLFDPSCA2CA1
SCHEMBL11693139 0.77 TP53 (0.48) TP53FDPSCA2CA1GPR84
SCHEMBL14431494 0.77 PTPN1 (0.40) TP53RECQLFDPSCA2CA1
SCHEMBL5155590 0.77 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115485878-A Nonaqueous electrolyte electricity storage element and method for manufacturing nonaqueous electrolyte electricity storage element 株式会社杰士汤浅国际 2022-12-16 — — CN disclosed
US-8895582-B2 Certain chemical entities, compositions, and methods CYTOKINETICS, INC. (US) 2014-11-25 — — US disclosed
US-8759374-B2 Certain chemical entities, compositions, and methods CYTOKINETICS, INC. (US) 2014-06-24 — — US disclosed
US-20130053348-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS QIAN XIANGPING (US) 2013-02-28 — — US disclosed
US-20120135964-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS QIAN XIANGPING (US) 2012-05-31 — — US disclosed
US-8088793-B2 Certain chemical entities, compositions, and methods CYTOKINETICS, INC. (US) 2012-01-03 — — US disclosed
US-20090275537-A1 Certain chemical entities, compositions, and methods CYTOKINETICS, INC. 2009-11-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275537-A1 Certain chemical entities, compositions, and methods MYLK, MYH2, MYH10 TP53 2206/4885RECQL 597/4885FDPS 3701/4885
US-20120135964-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS MYLK, MYH2, MYH10 TP53 2206/4885RECQL 597/4885FDPS 3701/4885
US-20130053348-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS MYLK, MYH2, MYH10 TP53 2206/4885RECQL 597/4885FDPS 3701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.