Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052124 | 0.76 | ESR1 (0.41) | ESR1ALOX5KDM4EALDH1A1MAPT | |
| SCHEMBL1977984 | 0.73 | PTGS2 (0.58) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL14551466 | 0.72 | GABRA1 (0.60) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL16245770 | 0.71 | GABRA1 (0.46) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL9338131 | 0.71 | TDP1 (0.46) | GABRA1GABRB2PTGS2ALOX5KDM4E | |
| SCHEMBL17748577 | 0.70 | CA2 (0.48) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL2292664 | 0.68 | GABRA1 (0.71) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL11694943 | 0.68 | GABRA1 (0.46) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL6299434 | 0.68 | GABRA1 (0.50) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL17897206 | 0.68 | GABRA1 (0.50) | GABRA1GABRB2PTGS2PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279291-B1 | COFERONS AND METHODS OF MAKING AND USING THEM | UNIV CORNELL (US) | 2019-07-03 | — | — | EP | disclosed |