Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BAD | Q92934 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21119441 | 0.76 | GABRA1 (0.47) | ESR1KDM4EALDH1A1ALOX5MAPT | |
| SCHEMBL20052258 | 0.75 | BACE1 (0.42) | ESR1THRATHRBKDM4EALDH1A1 | |
| SCHEMBL20052222 | 0.75 | BACE1 (0.42) | ESR1THRATHRBKDM4EALDH1A1 | |
| SCHEMBL5376298 | 0.72 | ESR1 (0.54) | ESR1THRATHRBKDM4EALDH1A1 | |
| SCHEMBL25751730 | 0.72 | ESR1 (0.48) | ESR1ACE2THRATHRBKDM4E | |
| SCHEMBL20052268 | 0.70 | ESR1 (0.35) | ESR1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL17013416 | 0.69 | ESR1 (0.45) | ESR1ACE2THRATHRBKDM4E | |
| SCHEMBL16116520 | 0.68 | ESR1 (0.44) | ESR1ACE2THRATHRBMAPT | |
| SCHEMBL16116515 | 0.68 | ESR1 (0.44) | ESR1ACE2THRATHRB | |
| SCHEMBL24226063 | 0.67 | ESR1 (0.47) | ESR1ACE2THRATHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |