Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.63 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA5A | P35218 | 3/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 2/20 | 0.47 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3758635 | 0.88 | CA2 (0.66) | HSD17B1HSD17B2HDAC3HDAC1HDAC6 | |
| SCHEMBL21159739 | 0.81 | MIF (0.49) | HSD17B1HSD17B2HDAC3HDAC1HDAC6 | |
| SCHEMBL11904306 | 0.81 | CA1 (0.57) | HSD17B1HSD17B2HDAC3HDAC1HDAC6 | |
| SCHEMBL31530343 | 0.81 | CA1 (0.51) | HSD17B1HSD17B2HDAC3HDAC1HDAC6 | |
| SCHEMBL22833938 | 0.80 | CYP1B1 (0.63) | HSD17B1HSD17B2CA1CA2CA5A | |
| SCHEMBL21160019 | 0.79 | CDC7 (0.48) | HSD17B1HSD17B2HDAC3HDAC1HDAC6 | |
| SCHEMBL29531292 | 0.79 | CDC7 (0.48) | HSD17B1HSD17B2HDAC3HDAC1HDAC6 | |
| SCHEMBL28949786 | 0.79 | HSD17B1 (0.61) | HSD17B1HSD17B2CA1CA2CA5A | |
| SCHEMBL21122080 | 0.78 | STIM1 (0.65) | HSD17B1HSD17B2CA1CA2CA5A | |
| SCHEMBL17002341 | 0.78 | KEAP1 (0.58) | HSD17B1HSD17B2HDAC3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250075265-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | ROCHE SEQUENCING SOLUTIONS INC (US) | 2025-03-06 | — | — | US | claimed |
| US-11970731-B2 | Enhancement of nucleic acid polymerization by aromatic compounds | Roche Sequencing Solutions, Inc. (US) | 2024-04-30 | — | — | US | claimed |
| EP-3735409-B1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS INC (US) | 2023-06-21 | — | — | EP | claimed |
| EP-3994262-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Stratos Genomics Inc. (US) | 2022-05-11 | — | — | EP | claimed |
| US-20220112548-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Roche Sequencing Solutions, Inc. | 2022-04-14 | — | — | US | claimed |
| US-20210062251-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Roche Sequencing Solutions, Inc. | 2021-03-04 | — | — | US | claimed |
| WO-2020263703-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS, INC. (US) | 2020-12-30 | — | — | WO | claimed |
| EP-3735409-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Stratos Genomics Inc. (US) | 2020-11-11 | — | — | EP | claimed |
| WO-2019135975-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS INC. (US) | 2019-07-11 | — | — | WO | claimed |
| US-20250075265-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | ROCHE SEQUENCING SOLUTIONS INC (US) | 2025-03-06 | — | — | US | disclosed |
| US-11970731-B2 | Enhancement of nucleic acid polymerization by aromatic compounds | Roche Sequencing Solutions, Inc. (US) | 2024-04-30 | — | — | US | disclosed |
| EP-3735409-B1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS INC (US) | 2023-06-21 | — | — | EP | disclosed |
| EP-3994262-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Stratos Genomics Inc. (US) | 2022-05-11 | — | — | EP | disclosed |
| US-20220112548-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Roche Sequencing Solutions, Inc. | 2022-04-14 | — | — | US | disclosed |
| US-20210062251-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Roche Sequencing Solutions, Inc. | 2021-03-04 | — | — | US | disclosed |
| WO-2020263703-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020263703-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2019135975-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS INC. (US) | 2019-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210062251-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | POLN, POLB, POLRMT | HSD17B1 3522/4885HSD17B2 3960/4885HDAC3 4794/4885 |
| US-11970731-B2 | Enhancement of nucleic acid polymerization by aromatic compounds | POLN, POLB, POLRMT | HSD17B1 3522/4885HSD17B2 3960/4885HDAC3 4794/4885 |
| US-20250075265-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | POLN, POLB, POLRMT | HSD17B1 3522/4885HSD17B2 3960/4885HDAC3 4794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.