Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25681057 | 0.96 | NPC1 (0.48) | NPC1RAB9ATP53TSHRNFKB1 | |
| SCHEMBL25681050 | 0.92 | NPC1 (0.48) | NPC1RAB9ATP53TSHRNFKB1 | |
| SCHEMBL5050877 | 0.87 | CYP2A6 (0.52) | NPC1RAB9ATP53TSHRNFKB1 | |
| SCHEMBL8434860 | 0.84 | SERPINE1 (0.50) | RAB9ANUDT1ADORA2AADORA1CYP2A6 | |
| SCHEMBL21124583 | 0.83 | CYP1A2 (0.58) | TSHRSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL9862849 | 0.83 | NPC1 (0.50) | NPC1RAB9ATP53TSHRNFKB1 | |
| SCHEMBL28322994 | 0.82 | METAP2 (0.48) | MEN1KMT2ACYP2A6KDM4E | |
| SCHEMBL30080985 | 0.82 | METAP2 (0.48) | MEN1KMT2ACYP2A6KDM4E | |
| SCHEMBL25681090 | 0.82 | SERPINE1 (0.49) | RAB9ANUDT1ADORA2AADORA1CYP2A6 | |
| SCHEMBL23823574 | 0.82 | GABRP (0.49) | NPC1RAB9ATP53TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190207117-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190207117-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | MAOA, MAOB, COMT | NPC1 2878/4885RAB9A 2251/4885TP53 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.