Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NAMPT | P43490 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.50 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13918749 | 0.87 | KDM4E (0.70) | KDM4EKMT2ANAMPTL3MBTL1CHRNA10 | |
| SCHEMBL6983630 | 0.84 | KDM4E (0.58) | KDM4EKMT2ANAMPTL3MBTL1CHRNA10 | |
| SCHEMBL12266946 | 0.84 | KMT2A (0.58) | KDM4EKMT2ANAMPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL13092061 | 0.84 | MAOB (0.66) | KDM4EKMT2ANAMPTALDH1A1NFKB1 | |
| SCHEMBL6975868 | 0.84 | HDAC3 (0.60) | KDM4EKMT2ANAMPTL3MBTL1CHRNA10 | |
| SCHEMBL23663764 | 0.82 | ALDH1A1 (0.73) | KDM4EKMT2ANAMPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL10294734 | 0.82 | KDM4E (0.57) | KDM4EKMT2ANAMPTL3MBTL1CHRNA10 | |
| SCHEMBL1290599 | 0.81 | LMNA (0.68) | KDM4EKMT2ANAMPTL3MBTL1ALDH1A1 | |
| SCHEMBL2977016 | 0.81 | KDM4E (0.65) | KDM4EKMT2ANAMPTL3MBTL1CHRNA10 | |
| SCHEMBL14350257 | 0.81 | KDM4E (0.64) | KDM4EKMT2ANAMPTL3MBTL1CHRNA10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11226337-B2 | Chemoproteomic profiling of protein electrophilic and oxidative post-translational modifications | Zenagem, LLC (US) | 2022-01-18 | — | — | US | disclosed |
| US-20190204336-A1 | CHEMOPROTEOMIC PROFILING OF PROTEIN ELECTROPHILIC AND OXIDATIVE POST-TRANSLATIONAL MODIFICATIONS | Zenagem, LLC | 2019-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190204336-A1 | CHEMOPROTEOMIC PROFILING OF PROTEIN ELECTROPHILIC AND OXIDATIVE POST-TRANSLATIONAL MODIFICATIONS | PTMS, CHAMP1, STUB1 | KDM4E 3113/4885KMT2A 1764/4885NAMPT 2826/4885 |
| US-11226337-B2 | Chemoproteomic profiling of protein electrophilic and oxidative post-translational modifications | PTMS, CHAMP1, STUB1 | KDM4E 3113/4885KMT2A 1764/4885NAMPT 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.