SCHEMBL21130396

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19914355	0.85	MAPT (0.54)	MAPTSMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL259112	0.85	IRAK4 (0.61)	MAPTSMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL19914352	0.84	TDP1 (0.66)	MAPTSMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL21066417	0.81	MAPT (0.67)	MAPTSMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL29496401	0.75	GRM4 (1.00)	SMN1; SMN2THRBGRM4HDAC6KDR
	SCHEMBL2530324	0.75	GRM4 (1.00)	SMN1; SMN2THRBGRM4HDAC6KDR
	SCHEMBL3595563	0.75	L3MBTL1 (0.77)	MAPTSMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL21130623	0.74	L3MBTL1 (0.57)	MAPTSMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL31216498	0.74	MAPT (0.71)	MAPTSMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL12268076	0.74	RAB9A (0.58)	MAPTSMN1; SMN2MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.