Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187057 | 0.75 | TRPM4 (0.56) | KDM4EHPGDMAPTHSD17B10MEN1 | |
| SCHEMBL5555424 | 0.69 | GPR84 (0.41) | KDM4EHPGDMAPTALOX15CYP3A4 | |
| SCHEMBL29975451 | 0.67 | KDM4E (0.39) | KDM4EHPGDMAPTALOX15CYP3A4 | |
| SCHEMBL25132403 | 0.63 | — | — | |
| SCHEMBL2639080 | 0.63 | DAO (0.61) | KDM4EHPGDMAPTHSD17B10TP53 | |
| SCHEMBL6468003 | 0.63 | KDM4E (0.53) | KDM4EHPGDMAPTALOX15CYP3A4 | |
| SCHEMBL29658219 | 0.63 | KDM4E (0.40) | KDM4EHPGDMAPTCYP3A4HSD17B10 | |
| SCHEMBL10524061 | 0.62 | HTT (0.41) | KDM4EMAPTHSD17B10TP53MEN1 | |
| SCHEMBL29966031 | 0.61 | KDM4E (0.59) | KDM4EHPGDMAPTALOX15CYP3A4 | |
| SCHEMBL1961365 | 0.61 | KDM4E (0.59) | KDM4EHPGDMAPTALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019115651-A1 | EXTRACT OF THE AERIAL PARTS OF LAWSONIA INERMIS AND ITS PREPARATION METHOD | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2019-06-20 | — | — | WO | disclosed |