Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.59 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.59 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.59 |
| ▸ | TNKS | O95271 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.59 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.59 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29966031 | 1.00 | KDM4E (0.59) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL2483048 | 0.76 | KDM4E (0.56) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL30503392 | 0.76 | KDM4E (0.56) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL31622431 | 0.76 | TNKS (0.53) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL31622430 | 0.76 | TNKS (0.53) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL24969553 | 0.75 | TNKS (0.59) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL1943194 | 0.75 | KDM4E (0.59) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL123427 | 0.75 | TNKS (0.59) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL3456369 | 0.75 | TNKS (0.56) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL294054 | 0.75 | TNKS (0.56) | KDM4EUSP2CSNK2A2PTGS1CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240315965-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2024-09-26 | — | — | US | claimed |
| CN-118086421-A | Application of agilawood endophyte in catalyzing chromone to produce hydroxychromone | 中国科学院昆明植物研究所 | 2024-05-28 | — | — | CN | claimed |
| EP-4157811-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | McMaster University (CA) | 2023-04-05 | — | — | EP | claimed |
| WO-2022182527-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | claimed |
| WO-2021237371-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2021-12-02 | — | — | WO | claimed |
| CN-110496163-A | The preparation method of citrous bud or flower or branch or leaf or fruit active component or ingredient and its application in medicine preparation | UNIV JIANGXI TRADITIONAL CHINESE MEDICINE | 2019-11-26 | — | — | CN | claimed |
| CN-110064002-A | Flores aurantii and branches and leaves active component or ingredient improve sleep or antidepression in preparation or improve the application in failure of memory drug or food | 江西中医药大学 | 2019-07-30 | — | — | CN | claimed |
| CN-109745384-A | The application and preparation method thereof of bitter orange flower active component or effective component in preparation treatment cardio-cerebrovascular ischemic disease drug | 江西中医药大学 | 2019-05-14 | — | — | CN | claimed |
| WO-2013013901-A1 | PROCESS FOR TREATING HUMAN PERSPIRATION USING POLYPHENOLS AND AN ENZYMATIC AND/OR CHEMICAL CATALYTIC OXIDATION SYSTEM | L'OREAL (FR) | 2013-01-31 | — | — | WO | claimed |
| WO-2011073941-A1 | USE OF A POLYMER AS AN ANTIOXIDANT AGENT | L'OREAL (FR) | 2011-06-23 | — | — | WO | claimed |
| EP-1352635-A2 | Composition for dyeing keratinous fibres comprising a system which restricts the transcutaneous passage of an oxidation dye | L'OREAL (FR) | 2003-10-15 | — | — | EP | claimed |
| EP-1348421-A2 | A method of thickening and styling human keratinous fibres using a particular catalytic system | L'OREAL (FR) | 2003-10-01 | — | — | EP | claimed |
| US-20030163878-A1 | Dyeing composition, method for obtaining the same and use for colouring the skin and/or keratinous fibres | L'OREAL (FR) | 2003-09-04 | — | — | US | claimed |
| US-20030103917-A1 | Dyeing composition promoting natural pigmentation, method for obtaining same and use for colouring the skin and/or keratinous fibres | L'OREAL (FR) | 2003-06-05 | — | — | US | claimed |
| US-20020124330-A1 | Coloration composition, process for obtaining the same and its use for the coloration of keratin fibres | L'OREAL (FR) | 2002-09-12 | — | — | US | claimed |
| EP-1229892-A1 | DYEING COMPOSITION, METHOD FOR OBTAINING SAME AND USE FOR COLOURING THE SKIN AND/OR KERATINOUS FIBRES | L'OREAL (FR) | 2002-08-14 | — | — | EP | claimed |
| EP-1229890-A1 | DYEING COMPOSITION PROMOTING NATURAL PIGMENTATION, METHOD FOR OBTAINING SAME AND USE FOR COLOURING THE SKIN AND/OR KERATINOUS FIBRES | L'OREAL (FR) | 2002-08-14 | — | — | EP | claimed |
| EP-1210931-A1 | Keratinic fibres dyeing composition | L'OREAL (FR) | 2002-06-05 | — | — | EP | claimed |
| WO-2002030371-A1 | DYEING COMPOSITION PROMOTING NATURAL PIGMENTATION, METHOD FOR OBTAINING SAME AND USE FOR COLOURING THE SKIN AND/OR KERATINOUS FIBRES | L"OREAL (FR) | 2002-04-18 | — | — | WO | claimed |
| WO-2002030375-A1 | DYEING COMPOSITION, METHOD FOR OBTAINING SAME AND USE FOR COLOURING THE SKIN AND/OR KERATINOUS FIBRES | L"OREAL (FR) | 2002-04-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030103917-A1 | Dyeing composition promoting natural pigmentation, method for obtaining same and use for colouring the skin and/or keratinous fibres | TYR, KRT18, POLR1C | KDM4E 3480/4885USP2 3218/4885CSNK2A2 610/4885 |
| US-20030163878-A1 | Dyeing composition, method for obtaining the same and use for colouring the skin and/or keratinous fibres | KRT18, HAO2, TYR | KDM4E 2350/4885USP2 2799/4885CSNK2A2 308/4885 |
| US-20020124330-A1 | Coloration composition, process for obtaining the same and its use for the coloration of keratin fibres | KRT18, TYR, OAT | KDM4E 611/4885USP2 2668/4885CSNK2A2 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.