SCHEMBL21132501

SCHEMBL21132501

COc1ccc(CONCl)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.55
AGXT P21549 2/20 0.55
APP P05067 5/20 0.48
HTT P42858 1/20 0.48
MAOB P27338 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CALM1 P0DP23 1/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
CMA1 P23946 1/20 0.46
LTA4H P09960 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7047450 0.83 IDO1 (0.59) IDO1AGXTAPPHTTMAOB
SCHEMBL28733742 0.81 IDO1 (0.57) IDO1AGXTAPPHTTMAOB
Hydrochloric Acid SCHEMBL29620934 0.79 IDO1 (0.59) IDO1AGXTAPPHTTMAOB
SCHEMBL28733756 0.78 IDO1 (0.53) IDO1AGXTAPPHTTMAOB
SCHEMBL1608953 0.78 IDO1 (0.53) IDO1AGXTAPPHTTMAOB
SCHEMBL1853891 0.76 IDO1 (0.61) IDO1AGXTAPPMAOBNPC1
SCHEMBL34413 0.75 IDO1 (0.67) IDO1AGXTAPPHTTMAOB
SCHEMBL31270 0.75 IDO1 (0.67) IDO1AGXTAPPHTTMAOB
SCHEMBL28733774 0.75 IDO1 (0.50) IDO1AGXTAPPHTTMAOB
SCHEMBL6634889 0.74 ALDH1A1 (0.57) IDO1HTTNPC1RAB9ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3089986-B1 CRYSTALLINE SALTS OF (Z)-O-OCTADEC-9-EN-1-YL O,O-DIHYDROGEN PHOSPHOROTHIOATE RXBIO INC (US) 2019-06-26 EP disclosed