Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 4/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22042801 | 0.79 | CA2 (0.41) | — | |
| SCHEMBL19018398 | 0.77 | GRM4 (0.34) | GRM4USP2TSHRNPY1RNPY2R | |
| SCHEMBL24179939 | 0.69 | MMP8 (0.38) | TSHR | |
| SCHEMBL19263663 | 0.67 | PRKCA (0.35) | — | |
| SCHEMBL2551899 | 0.66 | PRKCA (0.35) | — | |
| SCHEMBL106425 | 0.65 | CA2 (0.48) | — | |
| SCHEMBL21732967 | 0.65 | KDM4E (0.37) | TSHR | |
| SCHEMBL21441721 | 0.65 | PRKCA (0.30) | TSHR | |
| SCHEMBL19263665 | 0.65 | PRKCA (0.33) | — | |
| SCHEMBL13641645 | 0.64 | HMGCR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558538-B1 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | KODIAK SCIENCES INC (US) | 2019-07-03 | — | — | EP | disclosed |