Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14713359 | 0.81 | PRKCA (0.38) | PRKCAALDH1A1MAPT | |
| SCHEMBL19452182 | 0.81 | TSHR (0.44) | PRKCAALDH1A1PTGS1 | |
| SCHEMBL24179939 | 0.81 | MMP8 (0.38) | PRKCACYP1A2ALDH1A1 | |
| SCHEMBL14195308 | 0.80 | HMGCR (0.35) | PRKCAGABRR1CYP1A2FOLH1NAALAD2 | |
| SCHEMBL19263663 | 0.78 | PRKCA (0.35) | PRKCAALDH1A1 | |
| SCHEMBL5769217 | 0.78 | GABRR1 (0.35) | PRKCAGABRR1CYP1A2FOLH1NAALAD2 | |
| SCHEMBL19452281 | 0.76 | MAPT (0.46) | PRKCAELANEMAPT | |
| SCHEMBL21441721 | 0.75 | PRKCA (0.30) | PRKCA | |
| SCHEMBL21732967 | 0.75 | KDM4E (0.37) | PRKCA | |
| SCHEMBL19263665 | 0.75 | PRKCA (0.33) | PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3549963-A2 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | Kodiak Sciences Inc. (US) | 2019-10-09 | — | — | EP | disclosed |
| EP-2512462-B1 | MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC (US) | 2017-08-23 | — | — | EP | disclosed |
| EP-2558538-A2 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | Oligasis (US) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011130694-A2 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | OLIGASIS (US) | 2011-10-20 | — | — | WO | disclosed |