Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | CNOT7 | Q9UIV1 | 7/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14507745 | 0.88 | ALDH1A1 (0.57) | ALDH1A1LMNACYP3A4MAPTTSHR | |
| SCHEMBL13217674 | 0.83 | ALDH1A1 (0.66) | ALDH1A1LMNACYP3A4MAPTTSHR | |
| SCHEMBL4534193 | 0.80 | LMNA (0.62) | ALDH1A1LMNACYP3A4MAPTTSHR | |
| SCHEMBL13659011 | 0.79 | ALDH1A1 (0.60) | ALDH1A1LMNACYP3A4MAPTTSHR | |
| SCHEMBL659913 | 0.78 | TSHR (0.52) | ALDH1A1LMNACYP3A4MAPTTSHR | |
| SCHEMBL26439771 | 0.77 | LMNA (0.57) | ALDH1A1LMNACYP3A4MAPTTSHR | |
| SCHEMBL4532803 | 0.76 | ALDH1A1 (0.60) | ALDH1A1LMNACYP3A4MAPTTSHR | |
| SCHEMBL27462802 | 0.76 | ALDH1A1 (0.60) | ALDH1A1LMNACYP3A4MAPTTSHR | |
| SCHEMBL3843737 | 0.76 | ALDH1A1 (0.60) | ALDH1A1LMNACYP3A4MAPTTSHR | |
| SCHEMBL9299928 | 0.76 | LMNA (0.60) | ALDH1A1LMNACYP3A4MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10703754-B2 | Compounds and compositions for treating chemical warfare agent-induced injuries | ELI LILLY AND COMPANY (US) | 2020-07-07 | — | — | US | disclosed |
| US-20190194202-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELI LILLY AND COMPANY | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10703754-B2 | Compounds and compositions for treating chemical warfare agent-induced injuries | ELANE, CASP3, MMP8 | ALDH1A1 1104/4885LMNA 594/4885CYP3A4 2741/4885 |
| US-20190194202-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | ALDH1A1 1104/4885LMNA 594/4885CYP3A4 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.