Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.49 |
| ▸ | IAPP | P10997 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21133741 | 0.87 | APP (0.64) | APPIAPPALOX5NFKB1CYP3A4 | |
| SCHEMBL13562266 | 0.85 | APP (0.48) | APPIAPP | |
| SCHEMBL8409599 | 0.83 | IAPP (0.46) | APPIAPPCYP3A4 | |
| SCHEMBL8409601 | 0.83 | IAPP (0.46) | APPIAPPCYP3A4 | |
| SCHEMBL17527415 | 0.81 | CYP2D6 (0.71) | APPCYP1A2ALOX5CYP2D6NFKB1 | |
| SCHEMBL17527436 | 0.81 | CYP2D6 (0.71) | APPCYP1A2ALOX5CYP2D6NFKB1 | |
| SCHEMBL5702708 | 0.81 | CYP2D6 (0.69) | APPCYP1A2ALOX5CYP2D6NFKB1 | |
| SCHEMBL29929008 | 0.81 | CYP2D6 (0.69) | APPCYP1A2ALOX5CYP2D6NFKB1 | |
| SCHEMBL30334920 | 0.81 | CYP2D6 (0.69) | APPCYP1A2ALOX5CYP2D6NFKB1 | |
| SCHEMBL30335087 | 0.81 | CYP2D6 (0.69) | APPCYP1A2ALOX5CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10342766-B2 | 6-shogaol derivatives and activities thereof | NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY (US) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10342766-B2 | 6-shogaol derivatives and activities thereof | NFE2L2, HMOX1, KEAP1 | APP 2220/4885IAPP 2526/4885CYP1A2 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.