Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.64 |
| ▸ | IAPP | P10997 | 4/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 3/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21133740 | 0.87 | APP (0.49) | APPIAPPCYP3A4ALOX5NFKB1 | |
| SCHEMBL17527436 | 0.86 | CYP2D6 (0.71) | APPPTGS1KDM4EHSD17B10MEN1 | |
| SCHEMBL17527415 | 0.86 | CYP2D6 (0.71) | APPPTGS1KDM4EHSD17B10MEN1 | |
| SCHEMBL29929008 | 0.85 | CYP2D6 (0.69) | APPPTGS1KDM4EHSD17B10MEN1 | |
| SCHEMBL29929370 | 0.85 | CYP2D6 (0.69) | APPPTGS1KDM4EHSD17B10MEN1 | |
| SCHEMBL30335087 | 0.85 | CYP2D6 (0.69) | APPPTGS1KDM4EHSD17B10MEN1 | |
| SCHEMBL5702708 | 0.85 | CYP2D6 (0.69) | APPPTGS1KDM4EHSD17B10MEN1 | |
| SCHEMBL30334920 | 0.85 | CYP2D6 (0.69) | APPPTGS1KDM4EHSD17B10MEN1 | |
| SCHEMBL9681197 | 0.84 | APP (0.59) | APPIAPPPTGS1TTRDPP4 | |
| SCHEMBL8848105 | 0.84 | APP (0.59) | APPIAPPPTGS1TTRDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10342766-B2 | 6-shogaol derivatives and activities thereof | NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY (US) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10342766-B2 | 6-shogaol derivatives and activities thereof | NFE2L2, HMOX1, KEAP1 | APP 2220/4885IAPP 2526/4885PTGS1 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.