Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 5/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21133664 | 0.84 | CYP1A2 (0.53) | CYP1A2CYP2D6HTR1AHTR2CHTR2A | |
| SCHEMBL17527415 | 0.71 | CYP2D6 (0.71) | CYP1A2CYP2D6HTR1AALOX5NFKB1 | |
| SCHEMBL17527436 | 0.71 | CYP2D6 (0.71) | CYP1A2CYP2D6HTR1AALOX5NFKB1 | |
| SCHEMBL16610417 | 0.71 | KDM4E (0.48) | HTR1AHTR2CHTR2ASLC6A4HTR7 | |
| SCHEMBL29929370 | 0.70 | CYP2D6 (0.69) | CYP1A2CYP2D6HTR1AALOX5NFKB1 | |
| SCHEMBL30335087 | 0.70 | CYP2D6 (0.69) | CYP1A2CYP2D6HTR1AALOX5NFKB1 | |
| SCHEMBL29929008 | 0.70 | CYP2D6 (0.69) | CYP1A2CYP2D6HTR1AALOX5NFKB1 | |
| SCHEMBL30334920 | 0.70 | CYP2D6 (0.69) | CYP1A2CYP2D6HTR1AALOX5NFKB1 | |
| SCHEMBL5702708 | 0.70 | CYP2D6 (0.69) | CYP1A2CYP2D6HTR1AALOX5NFKB1 | |
| SCHEMBL16610368 | 0.70 | KDM4E (0.72) | CYP1A2HTR1AHTR2CKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10342766-B2 | 6-shogaol derivatives and activities thereof | NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY (US) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10342766-B2 | 6-shogaol derivatives and activities thereof | NFE2L2, HMOX1, KEAP1 | CYP1A2 267/4885CYP2D6 71/4885CYP1A1 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.