Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RBP1 | P09455 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18871870 | 1.00 | L3MBTL1 (0.40) | L3MBTL1NPC1HPGDMAPK1RAB9A | |
| SCHEMBL22763818 | 0.97 | L3MBTL1 (0.38) | L3MBTL1NPC1HPGDMAPK1RAB9A | |
| SCHEMBL18435651 | 0.95 | L3MBTL1 (0.37) | L3MBTL1NPC1HPGDMAPK1RAB9A | |
| SCHEMBL21925999 | 0.93 | ALDH1A1 (0.36) | L3MBTL1NPC1HPGDMAPK1RAB9A | |
| Acetic Acid SCHEMBL1228704 | 0.92 | GPR84 (0.36) | L3MBTL1NPC1HPGDMAPK1RAB9A | |
| Acetic Acid SCHEMBL1229754 | 0.90 | GPR84 (0.36) | L3MBTL1NPC1HPGDMAPK1RAB9A | |
| SCHEMBL18946268 | 0.89 | L3MBTL1 (0.32) | L3MBTL1NPC1HPGDMAPK1RAB9A | |
| Acetic Acid SCHEMBL1229607 | 0.87 | GPR84 (0.36) | L3MBTL1NPC1HPGDMAPK1RAB9A | |
| SCHEMBL22763970 | 0.86 | NPC1 (0.35) | NPC1HPGDMAPK1RAB9AHTT | |
| Acetic Acid SCHEMBL1229313 | 0.85 | GPR84 (0.36) | L3MBTL1NPC1HPGDMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10343999-B2 | Method for synthesizing enantiomerically pure N-(pyridin-4-yl)-2-hydroxy-alkylamide derivatives | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10343999-B2 | Method for synthesizing enantiomerically pure N-(pyridin-4-yl)-2-hydroxy-alkylamide derivatives | HACL2, NAAA, CYP1A2 | L3MBTL1 4831/4885NPC1 2041/4885HPGD 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.