Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
| ▸ | PDE1A | P54750 | 3/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.32 |
| ▸ | CFTR | P13569 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | PDE6C | P51160 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1767742 | 0.81 | ADORA2A (0.39) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL5503490 | 0.80 | ADORA2A (0.49) | ADORA2AADORA2BPDE2APDE1APDE1B | |
| SCHEMBL2113440 | 0.80 | ADORA2A (0.41) | ADORA2AADORA2BPDE2APDE1APDE1B | |
| SCHEMBL7672440 | 0.79 | GAA (0.36) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL10863614 | 0.79 | ADORA2A (0.38) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL6434440 | 0.79 | PNP (0.50) | ADORA2AADORA2BTSHRPDE4APDE4B | |
| SCHEMBL6268075 | 0.79 | ADORA2A (0.34) | ADORA2AADORA2BPDE2APDE1APDE1B | |
| SCHEMBL874734 | 0.78 | ADORA2A (0.45) | ADORA2AADORA2BCYP1A2TSHRPDE4A | |
| SCHEMBL9960806 | 0.78 | PNP (0.38) | ADORA2AADORA2BCYP1A2PDE4APDE4B | |
| SCHEMBL6271387 | 0.78 | CDK1 (0.37) | ADORA2AADORA2BPDE2APDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8679454-B2 | Particle immobilized coatings and uses thereof | SURMODICS, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-8158106-B2 | Drug delivery; microparticles immobilized on polymer surface | SURMODICS, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-20090186070-A1 | Particle immobilized coating and uses thereof | Surmodics Coatings, LLC | 2009-07-23 | — | — | US | disclosed |
| EP-1434571-B1 | PARTICLE IMMOBILIZED COATINGS AND USES THEREOF | SURMODICS INC (US) | 2005-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186070-A1 | Particle immobilized coating and uses thereof | SELP, SELPLG, PLAUR | ADORA2A 2202/4885ADORA2B 3270/4885PDE2A 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.