Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.49 |
| ▸ | PDE2A | O00408 | 6/20 | 0.47 |
| ▸ | PDE1A | P54750 | 4/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.47 |
| ▸ | CFTR | P13569 | 2/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | PDE6C | P51160 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874734 | 0.84 | ADORA2A (0.45) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL17186378 | 0.83 | PNP (0.39) | ADORA2AADORA2BPDE2APDE1APDE1B | |
| SCHEMBL18605634 | 0.83 | PNP (0.39) | ADORA2AADORA2BPDE2APDE1APDE1B | |
| SCHEMBL9960806 | 0.83 | PNP (0.38) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL17186422 | 0.82 | PNP (0.39) | ADORA2AADORA2BPDE2APDE1APDE1B | |
| SCHEMBL21748352 | 0.82 | ADORA2A (0.40) | ADORA2AADORA2BADORA1SMN1; SMN2PNP | |
| SCHEMBL6268075 | 0.81 | ADORA2A (0.34) | ADORA2AADORA2BPDE2APDE1APDE1B | |
| SCHEMBL667794 | 0.81 | PDE4A (0.49) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL6271387 | 0.80 | CDK1 (0.37) | ADORA2AADORA2BPDE2APDE1APDE1B | |
| SCHEMBL2113436 | 0.80 | ADORA2A (0.33) | ADORA2AADORA2BPDE2APDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977767-B1 | AMINOOXY-MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 2007-09-19 | — | — | EP | claimed |
| JP-60199899-A | — | — | None | — | — | JP | disclosed |
| JP-S60199899-A | NUCLEOSIDE 3'-PHOSPHOTRIESTER DERIVATIVE | FUJIREBIO INC | 1985-10-09 | — | — | JP | disclosed |