Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.41 |
| ▸ | CDK1 | P06493 | 7/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.40 |
| ▸ | CDK2 | P24941 | 7/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.40 |
| ▸ | CFTR | P13569 | 2/20 | 0.40 |
| ▸ | MGMT | P16455 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | PDE1A | P54750 | 2/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15013384 | 0.85 | MEN1 (0.40) | ADORA2AADORA2BCDK1CCNB1CCNA2 | |
| SCHEMBL3512359 | 0.84 | PDE4A (0.37) | ADORA2AADORA2BCDK1CCNB1CCNA2 | |
| SCHEMBL20497218 | 0.84 | CDK1 (0.36) | ADORA2AADORA2BCDK1CCNB1CCNA2 | |
| SCHEMBL2343362 | 0.83 | ADORA2A (0.44) | ADORA2AADORA2BCDK1CCNB1CCNA2 | |
| SCHEMBL2249888 | 0.82 | ADORA2A (0.39) | ADORA2AADORA2BCDK1CCNB1CCNA2 | |
| SCHEMBL1767750 | 0.81 | ADORA2A (0.47) | ADORA2AADORA2BCDK1CCNB1CCNA2 | |
| SCHEMBL5504400 | 0.80 | ADORA2A (0.59) | ADORA2AADORA2BCDK1CCNB1CCNA2 | |
| SCHEMBL2113436 | 0.80 | ADORA2A (0.33) | ADORA2AADORA2BCFTRPDE2APDE1A | |
| SCHEMBL10421281 | 0.80 | CDK1 (0.49) | ADORA2AADORA2BCDK1CCNB1CCNA2 | |
| SCHEMBL7672454 | 0.79 | MGMT (0.41) | ADORA2AADORA2BCDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528851-A | Pharmaceutical formulation of griseofulvin for long-term ocular delivery | 普渡研究基金会 | 2023-08-01 | — | — | CN | disclosed |
| CN-112138212-B | Active extracellular matrix, composition containing active extracellular matrix, 3D tissue repair scaffold, preparation method and application | 上海市东方医院（同济大学附属东方医院） | 2023-01-10 | — | — | CN | disclosed |
| CN-112138212-A | Active extracellular matrix, composition containing active extracellular matrix, 3D tissue repair scaffold, preparation method and application | 上海市东方医院（同济大学附属东方医院） | 2020-12-29 | — | — | CN | disclosed |
| US-8679454-B2 | Particle immobilized coatings and uses thereof | SURMODICS, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-8158106-B2 | Drug delivery; microparticles immobilized on polymer surface | SURMODICS, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-7794751-B2 | Medicament incorporation matrix | SURMODICS, INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20090186070-A1 | Particle immobilized coating and uses thereof | Surmodics Coatings, LLC | 2009-07-23 | — | — | US | disclosed |
| US-20080213334-A1 | Mixture of cationic polymer, anionic polymer and drug, that forms blended coatings and/or hydrogel coatings for controlled release of said drug from medical devices coated with or containing such media | Surmodics Coatings, LLC | 2008-09-04 | — | — | US | disclosed |
| US-20080089919-A1 | Such as heparin cofactor II binding activity; antithromin | W. L. GORE & ASSOCIATES, INC. | 2008-04-17 | — | — | US | disclosed |
| US-20060216324-A1 | Composition and method for preparing biocompatible surfaces | Surmodics Coatings, LLC | 2006-09-28 | — | — | US | disclosed |
| US-20060165751-A1 | Medicament incorporation matrix | Surmodics Coatings, LLC | 2006-07-27 | — | — | US | disclosed |
| US-20050281857-A1 | Methods and reagents for preparing biomolecule-containing coatings | Surmodics Coatings, LLC | 2005-12-22 | — | — | US | disclosed |
| US-20050220842-A1 | Coating compositions for bioactive agents | Surmodics Coatings, LLC | 2005-10-06 | — | — | US | disclosed |
| EP-1434571-B1 | PARTICLE IMMOBILIZED COATINGS AND USES THEREOF | SURMODICS INC (US) | 2005-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186070-A1 | Particle immobilized coating and uses thereof | SELP, SELPLG, PLAUR | ADORA2A 2202/4885ADORA2B 3270/4885CDK1 2652/4885 |
| US-20060216324-A1 | Composition and method for preparing biocompatible surfaces | F12, FGF23, C3AR1 | ADORA2A 754/4885ADORA2B 1110/4885CDK1 1457/4885 |
| US-20050220842-A1 | Coating compositions for bioactive agents | BMP2, FGF23, TGFB1 | ADORA2A 1277/4885ADORA2B 1829/4885CDK1 2103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.