Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18239228 | 0.91 | NAAA (0.47) | HSD17B10NAAAITGB3ITGA2BGNAI3 | |
| SCHEMBL18239264 | 0.83 | GNAI3 (0.49) | HSD17B10NAAAGNAI3GNAO1GNAI1 | |
| SCHEMBL18239218 | 0.83 | GNAI3 (0.49) | HSD17B10NAAAGNAI3GNAO1GNAI1 | |
| SCHEMBL24654167 | 0.73 | HSD17B10 (0.57) | HSD17B10NAAAITGB3ITGA2BALDH1A1 | |
| SCHEMBL24654069 | 0.71 | NAAA (0.59) | HSD17B10NAAAGNAI3GNAO1GNAI1 | |
| SCHEMBL25514716 | 0.70 | KMT2A (0.59) | ALDH1A1TSHRGAASMN1; SMN2 | |
| SCHEMBL22160653 | 0.70 | NAAA (0.61) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL22160533 | 0.70 | NAAA (0.61) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL22160676 | 0.70 | NAAA (0.61) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL22160679 | 0.70 | NAAA (0.61) | NAAAGNAI3GNAO1GNAI1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10342745-B2 | Methacrylamide compounds | OREGON HEALTH & SCIENCE UNIVERSITY | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10342745-B2 | Methacrylamide compounds | MAT2B, BHMT2, MMAB | HSD17B10 3594/4885NAAA 1494/4885ITGB3 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.