Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18239218 | 1.00 | GNAI3 (0.49) | GNAI3GNAO1GNAI1NAAAHSD17B10 | |
| SCHEMBL18239228 | 0.91 | NAAA (0.47) | GNAI3GNAO1GNAI1NAAAHSD17B10 | |
| SCHEMBL21134429 | 0.83 | HSD17B10 (0.43) | GNAI3GNAO1GNAI1NAAAHSD17B10 | |
| SCHEMBL18239211 | 0.79 | KEAP1 (0.43) | SMN1; SMN2NAMPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL18239213 | 0.77 | ALDH1A1 (0.45) | GNAI3GNAO1GNAI1NAAANAMPT | |
| SCHEMBL6357266 | 0.75 | GAA (0.59) | GNAI3GNAO1GNAI1NAAAHSD17B10 | |
| SCHEMBL18335491 | 0.74 | LMNA (0.47) | GNAI3GNAO1GNAI1NAAAHSD17B10 | |
| SCHEMBL20542868 | 0.74 | NAAA (0.61) | GNAI3GNAO1GNAI1NAAAGAA | |
| SCHEMBL24865972 | 0.73 | GNAI3 (0.50) | GNAI3GNAO1GNAI1NAAAHSD17B10 | |
| SCHEMBL10797412 | 0.73 | LMNA (0.49) | HSD17B10GAATSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183491-A1 | METHACRYLAMIDE COMPOUNDS | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2016-11-17 | — | — | WO | disclosed |