SCHEMBL21134865

SCHEMBL21134865

CC(C)C(C)(C(=O)OCCOC(=O)N1CCCCC1)C(C)C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.40
SMN1; SMN2 Q16637 4/20 0.37
NPC1 O15118 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
ALDH1A1 P00352 3/20 0.36
POLB P06746 2/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TSHR P16473 1/20 0.33
GAA P10253 1/20 0.33
EPHX1 P07099 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23397416 0.82 HPGD (0.37) HPGDSMN1; SMN2NPC1MAPTHTT
SCHEMBL18676261 0.82 POLB (0.40) HPGDSMN1; SMN2NPC1MAPTHTT
SCHEMBL18674257 0.79 POLB (0.40) HPGDSMN1; SMN2NPC1MAPTHTT
SCHEMBL17093002 0.77 SMN1; SMN2 (0.46) SMN1; SMN2HTTALDH1A1POLBLMNA
SCHEMBL5512792 0.75 HPGD (0.40) HPGDSMN1; SMN2NPC1MAPTHTT
SCHEMBL12925426 0.75 CHRNB2 (0.42) HPGDSMN1; SMN2HTTALDH1A1POLB
SCHEMBL19493323 0.74 ALDH1A1 (0.42) SMN1; SMN2HTTALDH1A1POLBLMNA
SCHEMBL5048847 0.74 LIPE (0.44) HPGDSMN1; SMN2HTTALDH1A1POLB
SCHEMBL16965702 0.73 HPGD (0.39) HPGDSMN1; SMN2NPC1MAPTHTT
SCHEMBL14999237 0.72 THRB (0.49) SMN1; SMN2NPC1MAPTHTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11829069-B2 Photoresist compositions and methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-11-28 US disclosed
US-20190204743-A1 PHOTORESIST COMPOSITIONS AND METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-07-04 US disclosed