Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21134791 | 0.88 | PTGS1 (0.35) | PTGS1GSTK1ACENOD1SLC7A11 | |
| SCHEMBL21134855 | 0.88 | PTGS1 (0.38) | PTGS1GSTK1ACENOD1SLC7A11 | |
| SCHEMBL21084939 | 0.87 | PTGS1 (0.40) | PTGS1GSTK1ACENOD1SLC7A11 | |
| SCHEMBL19934713 | 0.87 | PTGS1 (0.40) | PTGS1GSTK1ACENOD1SLC7A11 | |
| SCHEMBL21084936 | 0.87 | PTGS1 (0.40) | PTGS1GSTK1ACENOD1SLC7A11 | |
| SCHEMBL19934723 | 0.87 | PTGS1 (0.40) | PTGS1GSTK1ACENOD1SLC7A11 | |
| SCHEMBL16770307 | 0.87 | NOD1 (0.38) | PTGS1GSTK1DPP4DPP8DPP9 | |
| SCHEMBL19934772 | 0.83 | PTGS1 (0.43) | PTGS1GSTK1ACENOD1SLC7A11 | |
| SCHEMBL19934741 | 0.83 | PTGS1 (0.43) | PTGS1GSTK1ACENOD1SLC7A11 | |
| SCHEMBL21153867 | 0.83 | PTGS1 (0.43) | PTGS1GSTK1ACENOD1SLC7A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008286-B2 | Amino mercaptan compound and preparation method therefor and use thereof in protection against radiation | SHANGHAI KECHOW PHARMA, INC (CN) | 2021-05-18 | — | — | US | disclosed |
| US-20190202779-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | SHANGHAI KECHOW PHARMA, INC. (CN) | 2019-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190202779-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | MGMT, PRMT8, SULT1A1 | PTGS1 1697/4885GSTK1 751/4885ACE 4638/4885 |
| US-11008286-B2 | Amino mercaptan compound and preparation method therefor and use thereof in protection against radiation | MGMT, GSTA1, PRMT1 | PTGS1 455/4885GSTK1 260/4885ACE 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.